TCF3 anticorps (N-Term)

N° du produit ABIN2780485

Détail du produit anti-TCF3 anticorps

Antigène: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Porc, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCF3 est non-conjugé

Application: Western Blotting (WB)

Séquence: MNQPQRMAPV GTDKELSDLL DFSMMFPLPV TNGKGRPASL AGAQFGGSGL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 77%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TCF3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TCF3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 654 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TCF3

Antigène: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Autre désignation: TCF3 (TCF3 Produits)

Synonymes: anticorps E2A, anticorps E47, anticorps ITF1, anticorps TCF-3, anticorps VDIR, anticorps bHLHb21, anticorps tcf3a, anticorps zgc:113045, anticorps A1, anticorps AA408400, anticorps ALF2, anticorps AW209082, anticorps E12, anticorps E12/E47, anticorps ME2, anticorps Pan1, anticorps Pan2, anticorps Tcfe2a, anticorps bhlhb21, anticorps e2a, anticorps itf1, anticorps tcfe2a, anticorps vdir, anticorps xtcf-3, anticorps xtcf3, anticorps G12, anticorps TCF7L1, anticorps XE3, anticorps transcription factor 3, anticorps transcription factor 3b, anticorps transcription factor 3 L homeolog, anticorps transcription factor E2a, anticorps TCF3, anticorps tcf3b, anticorps Tcf3, anticorps tcf3.L, anticorps tcfe2a

Sujet: TCF3 contains 1 basic helix-loop-helix (bHLH) domain. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
Alias Symbols: E2A, E47, ITF1, VDIR, TCF-3, bHLHb21
Protein Interaction Partner: ID3, FAM115A, TLE1, RNF14, UBC, SCX, MAPKAPK2, MAPKAPK3, TCF21, Ube2i, ID2, FUS, CTNNB1, RPL37, MAX, USF1, TCF12, TCF3, MYOD1, Rufy1, Tfap4, Rpa1, Tbx6, Ncl, Twist2, SUPT3H, TRRAP, KAT2A, TADA2A, FOXH1, ELAVL1, TCF24, SETSIP, FLG2, BHLHA15, MYL6B, TIMM50,
Protein Size: 654

Poids moléculaire: 68 kDa

ID gène: 6929

NCBI Accession: NM_003200, NP_003191

UniProt: P15923

Pathways: Signalisation WNT, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response