MED26 anticorps (N-Term)

N° du produit ABIN2780622

Détail du produit anti-MED26 anticorps

Antigène: MED26 (Mediator Complex Subunit 26 (MED26))

Épitope: N-Term

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED26 est non-conjugé

Application: Western Blotting (WB)

Séquence: TAAPASPQQI RDRLLQAIDP QSNIRNMVAV LEVISSLEKY PITKEALEET

Homologie: Cow: 93%, Dog: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MED26. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MED26

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 600 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED26

Antigène: MED26 (Mediator Complex Subunit 26 (MED26))

Autre désignation: MED26 (MED26 Produits)

Synonymes: anticorps med26, anticorps wu:fe06c07, anticorps wu:fi75a09, anticorps zgc:55993, anticorps CRSP7, anticorps CRSP70, anticorps 5730493L18Rik, anticorps AI414941, anticorps AW495270, anticorps Crsp7, anticorps Slc35e1, anticorps crsp7, anticorps mediator of RNA polymerase II transcription subunit 26, anticorps cofactor required for Sp1 transcriptional activation, subunit 7, anticorps mediator complex subunit 26, anticorps mediator complex subunit 26 L homeolog, anticorps LOC725023, anticorps crsp7, anticorps MED26, anticorps Med26, anticorps med26.L

Sujet: MED26 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-261 AC024075.4 20290-20550 c 262-726 AF104253.1 1-465 727-3184 AK128435.1 1414-3871
Alias Symbols: CRSP7, CRSP70
Protein Interaction Partner: MED19, MED13, MED12, MED21, MED11, TAF8, MED8, MED30, EAF1, MED10, TAF3, MED25, MED28, ICE2, EAF2, MED29, MED9, MED18, MED15, MED31, MED4, AFF4, MED13L, ICE1, CDK19, ELL2, MED16, MED6, MED20, MED7, MED27, MED17, MED23, MED14, ELL, TAF15, TCEB3, TCEA1, TBP
Protein Size: 600

Poids moléculaire: 65 kDa

ID gène: 9441

NCBI Accession: NM_004831, NP_004822

UniProt: O95402

Pathways: Regulation of Lipid Metabolism by PPARalpha