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Butyrylcholinesterase anticorps (N-Term)

BCHE Reactivité: Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Mouton, Cobaye, Porc, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN310570
  • Antigène Voir toutes Butyrylcholinesterase (BCHE) Anticorps
    Butyrylcholinesterase (BCHE)
    Épitope
    • 15
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 66
    • 16
    • 14
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Chien, Rat, Boeuf (Vache), Cheval, Mouton, Cobaye, Porc, Lapin
    Hôte
    • 56
    • 21
    Lapin
    Clonalité
    • 55
    • 22
    Polyclonal
    Conjugué
    • 31
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Butyrylcholinesterase est non-conjugé
    Application
    • 60
    • 26
    • 22
    • 13
    • 13
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    SSLHVYDGKF LARVERVIVV SMNYRVGALG FLALPGNPEA PGNMGLFDQQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against BCHE. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human BCHE
    Top Product
    Discover our top product BCHE Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 602 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mizukami, Akatsu, Abrahamson, Mi, Ikonomovic: "Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 36, Issue 2, pp. 135-45, (2016) (PubMed).

  • Antigène
    Butyrylcholinesterase (BCHE)
    Autre désignation
    BCHE (BCHE Produits)
    Synonymes
    anticorps che, anticorps che1, anticorps bche, anticorps cholinesterase, anticorps CHE1, anticorps CHE2, anticorps E1, anticorps C730038G20Rik, anticorps butyrylcholinesterase L homeolog, anticorps butyrylcholinesterase, anticorps bche.L, anticorps bche, anticorps BCHE, anticorps Bche
    Sujet
    Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
    Alias Symbols: CHE1, E1
    Protein Interaction Partner: COLQ, BCHE,
    Protein Size: 602
    Poids moléculaire
    68 kDa
    ID gène
    590
    NCBI Accession
    NM_000055, NP_000046
    UniProt
    P06276
    Pathways
    Peptide Hormone Metabolism
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