RORA anticorps (N-Term)

N° du produit ABIN2782302

Détail du produit anti-RORA anticorps

Antigène: RORA (RAR-Related Orphan Receptor A (RORA))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORA est non-conjugé

Application: Western Blotting (WB)

Séquence: MESAPAAPDP AASEPGSSGS EAAAGSRETP LTQDTGRKSE APGAGRRQSY

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Rora. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Rora

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 523 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RORA

Antigène: RORA (RAR-Related Orphan Receptor A (RORA))

Autre désignation: Rora (RORA Produits)

Synonymes: anticorps ror1, anticorps ror2, anticorps ror3, anticorps rzra, anticorps nr1f1, anticorps MGC146531, anticorps NR1F1, anticorps ROR1, anticorps ROR2, anticorps ROR3, anticorps RZR-ALPHA, anticorps RZRA, anticorps RORalpha-B, anticorps gb:dq017624, anticorps rora2, anticorps 9530021D13Rik, anticorps Nr1f1, anticorps nmf267, anticorps sg, anticorps staggerer, anticorps tmgc26, anticorps RORalpha1, anticorps RAR related orphan receptor A, anticorps RAR-related orphan receptor A, anticorps RAR-related orphan receptor A, paralog a, anticorps RAR-related orphan receptor alpha, anticorps RORA, anticorps rora, anticorps Rora, anticorps roraa

Sujet: Rora is an orphan nuclear receptor. It binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. IT is a possible receptor for cholesterol or one of its derivatives.
Alias Symbols: 9530021D13Rik, Nr1f1, ROR1, ROR2, ROR3, nmf267, sg, staggerer, tmgc26
Protein Interaction Partner: Atxn1,
Protein Size: 523

Poids moléculaire: 59 kDa

ID gène: 19883

NCBI Accession: NM_013646, NP_038674

UniProt: P51448

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha