PRIM1 anticorps (N-Term)

N° du produit ABIN310748

Détail du produit anti-PRIM1 anticorps

Antigène: PRIM1 (Primase, DNA, Polypeptide 1 (49kDa) (PRIM1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRIM1 est non-conjugé

Application: Western Blotting (WB)

Séquence: SQYYRWLNYG GVIKNYFQHR EFSFTLKDDI YIRYQSFNNQ SDLEKEMQKM

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PRIM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRIM1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 420 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRIM1

Antigène: PRIM1 (Primase, DNA, Polypeptide 1 (49kDa) (PRIM1))

Autre désignation: PRIM1 (PRIM1 Produits)

Synonymes: anticorps AI324982, anticorps p49, anticorps dnapol-alpha50, anticorps DNA primase, p49 subunit, anticorps DNA primase subunit 1, anticorps DNA primase subunit 1 S homeolog, anticorps Prim1, anticorps PRIM1, anticorps prim1.S

Sujet: The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. PRIM1 is the small, 49 kDa primase subunit.The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit.
Alias Symbols: MGC12308, p49
Protein Interaction Partner: FAM96B, CIAO1, UBC, MMS19, MDC1, POLA2, PRIM2, POLE, POLA1, COPS6, RPA3, RPA2, RPA1, RAE1, MRPL38, TP53, XRCC5,
Protein Size: 420

Poids moléculaire: 50 kDa

ID gène: 5557

NCBI Accession: NM_000946, NP_000937

UniProt: P49642

Pathways: Telomere Maintenance, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, SARS-CoV-2 Protein Interactome