RFC4 anticorps (Middle Region)
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- Antigène Voir toutes RFC4 Anticorps
- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Porc, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RFC4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DKLEAVVKDL IDEGHAATQL VNQLHDVVVE NNLSDKQKSI ITEKLAEVDK
- Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against RFC4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RFC4
- Top Product
- Discover our top product RFC4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 363 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
- Autre désignation
- RFC4 (RFC4 Produits)
- Synonymes
- anticorps 44.t00003, anticorps 21.m03053, anticorps rfc4, anticorps A1, anticorps AI894123, anticorps AU040575, anticorps RFC37, anticorps rfc2, anticorps replication factor C subunit 4, anticorps Replication factor C subunit 4, anticorps replication factor C (activator 1) 4, anticorps replication factor C subunit 4 L homeolog, anticorps PFL2005w, anticorps EHI_167150, anticorps TP03_0432, anticorps Tb11.01.1310, anticorps BBOV_IV002210, anticorps rfc4, anticorps rfc-4, anticorps Rfc4, anticorps RFC4, anticorps rfc4.L
- Sujet
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The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Alias Symbols: A1, MGC27291, RFC37
Protein Interaction Partner: RNF41, UBC, RFC5, PCNA, TP53, SUMO2, RPA3, RPA2, RPA1, RNF2, C14orf166, RTCB, RPL26L1, DIMT1, NELFB, EDC4, IGF2BP3, EIF2B2, EIF2B3, YBX3, QARS, NMT1, HNRNPM, MRE11A, ILF2, HNRNPU, FLII, FKBP3, EPRS, DHX9, DDX1, ABCF1, PARK2, TARDBP, MPG, RFC2, MYC, FN1, P
Protein Size: 363 - Poids moléculaire
- 40 kDa
- ID gène
- 5984
- NCBI Accession
- NM_002916, NP_002907
- UniProt
- P35249
- Pathways
- Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA
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