WNT6 anticorps (Middle Region)

N° du produit ABIN405845

Détail du produit anti-WNT6 anticorps

Antigène: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Épitope: Middle Region

Reactivité: Humain, Souris, Lapin, Rat, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT6 est non-conjugé

Application: Western Blotting (WB)

Séquence: ERFHGASRVM GTNDGKALLP AVRTLKPPGR ADLLYAADSP DFCAPNRRTG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against WNT6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human WNT6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 365 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur WNT6

Antigène: WNT6 (Wingless-Type MMTV Integration Site Family, Member 6 (WNT6))

Autre désignation: WNT6 (WNT6 Produits)

Synonymes: anticorps WNT6, anticorps si:dkey-31m21.2, anticorps Wnt6, anticorps AA409270, anticorps Wnt-6, anticorps Xwnt-6, anticorps wnt-6, anticorps wnt6-A, anticorps xWnt6, anticorps Wnt family member 6, anticorps wingless-type MMTV integration site family, member 6b, anticorps wingless-type MMTV integration site family, member 6, anticorps Wnt family member 6 S homeolog, anticorps WNT6, anticorps Wnt6, anticorps wnt6b, anticorps wnt6.S

Sujet: The WNT family consists of several secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT6 is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The WNT6 protein overexpression may play key roles in carcinogenesis. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97 % identical to the mouse Wnt6 protein at the amino acid level.
Alias Symbols: -
Protein Interaction Partner: PORCN,
Protein Size: 365

Poids moléculaire: 37 kDa

ID gène: 7475

NCBI Accession: NM_006522, NP_006513

UniProt: Q9Y6F9

Pathways: Signalisation WNT, Tube Formation