PSMD8 anticorps (C-Term)

N° du produit ABIN2783285

Détail du produit anti-PSMD8 anticorps

Antigène: PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD8 est non-conjugé

Application: Western Blotting (WB)

Séquence: DYAKKRGWVL GPNNYYSFAS QQQKPEDTTI PSTELAKQVI EYARQLEMIV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PSMD8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMD8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 257 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PSMD8

Antigène: PSMD8 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))

Autre désignation: PSMD8 (PSMD8 Produits)

Synonymes: anticorps HIP6, anticorps HYPF, anticorps Nin1p, anticorps Rpn12, anticorps S14, anticorps p31, anticorps hip6, anticorps hypf, anticorps nin1p, anticorps rpn12, anticorps psmd8b, anticorps 6720456J22Rik, anticorps AA407360, anticorps AL033291, anticorps AL033322, anticorps AL033323, anticorps C76433, anticorps psmd8, anticorps psmd8a, anticorps fa93g07, anticorps fb17c09, anticorps fb49a10, anticorps zgc:86762, anticorps wu:fa93g07, anticorps wu:fb17c09, anticorps wu:fb49a10, anticorps PSMD8, anticorps proteasome 26S subunit, non-ATPase 8, anticorps proteasome 26S subunit, non-ATPase 8 S homeolog, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 8, anticorps proteasome 26S subunit, non-ATPase 8 L homeolog, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene, anticorps PSMD8, anticorps psmd8.S, anticorps Psmd8, anticorps psmd8.L, anticorps psmd8, anticorps LOC468490

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. PSMD8 is a non-ATPase subunit of the 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Alias Symbols: HIP6, HYPF, MGC1660, Nin1p, Rpn12, S14, p31
Protein Interaction Partner: HUWE1, UBC, PSMD14, TXNL1, PPFIA1, RPS21, RPS12, RPS8, PSMD11, PSMD7, PSMD4, PSMD3, PSMD2, PSMD1, PSMC6, PSMC5, PSMC4, PSMC2, PSMC1, MAP2, DYNC1I2, DHX9, ABCF1, KCMF1, UCHL5, DYNC1LI1, KIAA0368, ADRM1, HNRNPA0, PARK2, RNF11, BAG3, NOS2, SMAD9, SMAD2, PSMD
Protein Size: 257

Poids moléculaire: 27 kDa

ID gène: 5714

UniProt: P48556

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Proton Transport, Synthesis of DNA, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway