HLA-DQA2 anticorps (N-Term)

N° du produit ABIN2783759

Détail du produit anti-HLA-DQA2 anticorps

Antigène: HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Mouton, Boeuf (Vache), Chévre, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DQA2 est non-conjugé

Application: Western Blotting (WB)

Séquence: GVNFYQSHGP SGQYTHEFDG DEEFYVDLET KETVWQLPMF SKFISFDPQS

Homologie: Cow: 100%, Goat: 100%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 86%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HLA-DQA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HLA-DQA2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 255 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HLA-DQA2

Antigène: HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))

Autre désignation: HLA-DQA2 (HLA-DQA2 Produits)

Synonymes: anticorps DX-ALPHA, anticorps HLA-DXA, anticorps major histocompatibility complex, class II, DQ alpha 2, anticorps HLA-DQA2

Sujet: This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.
Alias Symbols: DQ alpha, HLA-DXA, DX-ALPHA
Protein Interaction Partner: UBC, HLA-DQB1, CD4, INS,
Protein Size: 255

Poids moléculaire: 28 kDa

ID gène: 3118

NCBI Accession: NM_020056, NP_064440

UniProt: P01906

Pathways: TCR Signaling