WNT3 anticorps (Middle Region)

N° du produit ABIN2783983

Détail du produit anti-WNT3 anticorps

Antigène: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT3 est non-conjugé

Application: Western Blotting (WB)

Séquence: SHHKGPPGEG WKWGGCSEDA DFGVLVSREF ADARENRPDA RSAMNKHNNE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against WNT3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human WNT3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 355 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur WNT3

Antigène: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Autre désignation: WNT3 (WNT3 Produits)

Synonymes: anticorps INT4, anticorps Ci-Wnt3, anticorps WNT3, anticorps int4, anticorps Xwnt3, anticorps wnt-3, anticorps wnt3l, anticorps Xwnt-3, anticorps wnt3, anticorps Int-4, anticorps Wnt-3, anticorps wnt3-A, anticorps Wnt family member 3, anticorps wingless-type MMTV integration site family, member 3, anticorps proto-oncogene Wnt-3, anticorps wingless-type MMTV integration site family member 3, anticorps Wnt family member 3A, anticorps wingless-type MMTV integration site family member 3 L homeolog, anticorps WNT3, anticorps Wnt3, anticorps wnt3, anticorps LOC468297, anticorps WNT3A, anticorps wnt3.L

Sujet: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Alias Symbols: INT4, MGC131950, MGC138321, MGC138323
Protein Interaction Partner: FZD1,
Protein Size: 355

Poids moléculaire: 37 kDa

ID gène: 7473

NCBI Accession: NM_030753, NP_110380

UniProt: P56703

Pathways: Signalisation WNT, Regulation of Cell Size