FBXO31 anticorps (Middle Region)
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- Antigène Voir toutes FBXO31 Anticorps
- FBXO31 (F-Box Protein 31 (FBXO31))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FBXO31 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- QGPRESQPSP AQPRAEAPSK GPDGTPGEDG GEPGDAVAAA EQPAQCGQGQ
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against FBXO31. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human FBXO31
- Top Product
- Discover our top product FBXO31 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 367 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FBXO31 (F-Box Protein 31 (FBXO31))
- Autre désignation
- FBXO31 (FBXO31 Produits)
- Synonymes
- anticorps 1110003O08Rik, anticorps 2310046N15Rik, anticorps Fbx14, anticorps Fbxo14, anticorps FBX14, anticorps FBXO14, anticorps Fbx31, anticorps pp2386, anticorps RGD1561069, anticorps fbx14, anticorps fbx31, anticorps fbxo14, anticorps fbxo31, anticorps F-box protein 31, anticorps F-box protein 31 S homeolog, anticorps F-box protein 31 L homeolog, anticorps Fbxo31, anticorps FBXO31, anticorps fbxo31, anticorps fbxo31.S, anticorps fbxo31.L
- Sujet
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FBXO31 is the component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. FBXO31 specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor.
Alias Symbols: DKFZP434B027, DKFZp434J1815, FBX14, FBXO14, FLJ22477, Fbx31, MGC15419, MGC9527, pp2386
Protein Interaction Partner: CDT1, UBE2L6, UBE2D1, CCND1, CUL1, MAP2K6, PARD6A, SKP1, COPS5, RBX1,
Protein Size: 367 - Poids moléculaire
- 40 kDa
- ID gène
- 79791
- NCBI Accession
- NM_024735, NP_079011
- UniProt
- Q5XUX0
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