RPS6KA2 anticorps (Middle Region)

N° du produit ABIN503865

Détail du produit anti-RPS6KA2 anticorps

Antigène: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cheval, Chien, Cobaye, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6KA2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LSRQDVHLVK GAMAATYFAL NRTPQAPRLE PVLSSNLAQR RGMKRLTSTR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against RPS6KA2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RPS6KA2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 733 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RPS6KA2

Antigène: RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))

Autre désignation: RPS6KA2 (RPS6KA2 Produits)

Synonymes: anticorps HU-2, anticorps MAPKAPK1C, anticorps RSK, anticorps RSK3, anticorps S6K-alpha, anticorps S6K-alpha2, anticorps p90-RSK3, anticorps pp90RSK3, anticorps 90kDa, anticorps D17Wsu134e, anticorps Rps6ka-rs1, anticorps Rsk3, anticorps p90rsk, anticorps pp90rsk, anticorps ribosomal protein S6 kinase A2, anticorps ribosomal protein S6 kinase, polypeptide 2, anticorps Rps6ka2, anticorps RPS6KA2

Sujet: RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3
Protein Interaction Partner: MAPK3, MAPK1, RPS6KA1, HSP90AA1, FLNC, CSNK2B, STXBP2, NQO2, UBC, RPS6KA2, JUN, FOS, SHANK1, BAD, MAGI1, L1CAM, MAP2K1, CREB1, CREBBP,
Protein Size: 733

Poids moléculaire: 81 kDa

ID gène: 6196

NCBI Accession: NM_021135, NP_066958

UniProt: Q15349

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades