MIF anticorps (Middle Region)

N° du produit ABIN2786654

Détail du produit anti-MIF anticorps

Antigène: MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Mouton, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PQYIAVHVVP DQLMAFGGSS EPCALCSLHS IGKIGGAQNR SYSKLLCGLL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against MIF. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MIF

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 115 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MIF

Antigène: MIF (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF))

Autre désignation: MIF (MIF Produits)

Synonymes: anticorps mif, anticorps Mif, anticorps gif, anticorps glif, anticorps mmif, anticorps LOC100136498, anticorps LOC100284350, anticorps LOC100284546, anticorps GIF, anticorps Glif, anticorps GLIF, anticorps MMIF, anticorps macrophage migration inhibitory factor L homeolog, anticorps macrophage migration inhibitory factor, anticorps macrophage migration inhibitory factor (glycosylation-inhibiting factor), anticorps mif.L, anticorps mif, anticorps MIF, anticorps Mif, anticorps PHATRDRAFT_49660, anticorps LOC100136498, anticorps cl405_1, anticorps LOC100284546

Sujet: This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
Alias Symbols: GIF, GLIF, MMIF
Protein Interaction Partner: WDYHV1, UBC, MIF, MDM2, ASB15, ZNF408, UPF2, BNIPL, HCVgp1, NGFRAP1, VCAM1, ITGA4, FN1, IGBP1, CLNS1A, COPS5, TP53, NME1, CDK2, STUB1, HSP90AA1, VHL, STRN4, COPS6, GORASP2, CD74, FIBP,
Protein Size: 115

Poids moléculaire: 12 kDa

ID gène: 4282

NCBI Accession: NM_002415, NP_002406

UniProt: P14174

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling