RAGE anticorps (N-Term)
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- Antigène Voir toutes RAGE (AGER) Anticorps
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RAGE est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MKQRFESIEQ VNNLREIQAL RRLNPHPNIL MLHEVVFDRK SGSLALICEL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against RAGE. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RAGE
- Top Product
- Discover our top product AGER Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 419 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-{kappa}B." dans: Carcinogenesis, Vol. 32, Issue 8, pp. 1167-75, (2011) (PubMed).
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Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-{kappa}B." dans: Carcinogenesis, Vol. 32, Issue 8, pp. 1167-75, (2011) (PubMed).
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- Antigène
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Autre désignation
- RAGE (AGER Produits)
- Synonymes
- anticorps RAGE, anticorps AGER, anticorps advanced glycosylation end-product specific receptor, anticorps advanced glycosylation end product-specific receptor, anticorps MAPK/MAK/MRK overlapping kinase, anticorps AGER, anticorps Ager, anticorps LOC719012
- Sujet
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RAGE is able to phosphorylate several exogenous substrates and to undergo autophosphorylation.
Alias Symbols: MOK, RAGE1, RAGE, RAGE-1
Protein Interaction Partner: UBC, WDR18, SDF4, HUWE1, ZNF223, MOK, INSR, MAPK6, MYC, JUN, CCNB1,
Protein Size: 419 - Poids moléculaire
- 48 kDa
- ID gène
- 5891
- NCBI Accession
- NM_013401, NP_055041
- UniProt
- Q9UQ07
- Pathways
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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