ERCC6L anticorps (N-Term)
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- Antigène Voir toutes ERCC6L Anticorps
- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
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Épitope
- N-Term
- Reactivité
- Humain, Rat, Cheval, Boeuf (Vache), Chien, Porc, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ERCC6L est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GDLEEAFKLF NLAKDIFPNE KVLSRIQKIQ EALEELAEQG DDEFTDVCNS
- Homologie
- Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 93%, Rat: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against ERCC6L. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC6L
- Top Product
- Discover our top product ERCC6L Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1250 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))
- Autre désignation
- ERCC6L (ERCC6L Produits)
- Synonymes
- anticorps PICH, anticorps RAD26L, anticorps BC004701, anticorps D330021P09Rik, anticorps RGD1565734, anticorps fc22h03, anticorps si:ch211-278b8.3, anticorps wu:fc22h03, anticorps ERCC excision repair 6 like, spindle assembly checkpoint helicase, anticorps excision repair cross-complementing rodent repair deficiency complementation group 6 like, anticorps DNA excision repair protein ERCC-6-like, anticorps excision repair cross-complementation group 6-like, anticorps ERCC6L, anticorps Ercc6l, anticorps LOC100373376, anticorps LOC100494766, anticorps LOC100552957, anticorps LOC100560751, anticorps LOC100563247, anticorps ercc6l
- Sujet
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ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint.ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
Alias Symbols: FLJ20105, MGC131695, PICH
Protein Interaction Partner: LMO4, UBC, HTT, BARD1, ACACA, Ercc6l, Plk1, RB1CC1, RPA3,
Protein Size: 1250 - Poids moléculaire
- 141 kDa
- ID gène
- 54821
- NCBI Accession
- NM_017669, NP_060139
- UniProt
- Q2NKX8
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