PRKACA anticorps (N-Term)

N° du produit ABIN2787416

Détail du produit anti-PRKACA anticorps

Antigène: PRKACA (Protein Kinase A, alpha (PRKACA))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Mouton, Porc, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKACA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MASNSSDVKE FLAKAKEDFL KKWESPAQNT AHLDQFERIK TLGTGSFGRV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PRKACA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKACA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 343 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRKACA

Antigène: PRKACA (Protein Kinase A, alpha (PRKACA))

Autre désignation: PRKACA (PRKACA Produits)

Synonymes: anticorps PKACA, anticorps Calpha, anticorps Cs-PKA, anticorps PKCA1, anticorps PKA, anticorps PKCD, anticorps Pkaca, anticorps zgc:158799, anticorps protein kinase cAMP-activated catalytic subunit alpha, anticorps protein kinase, cAMP dependent, catalytic, alpha, anticorps cAMP-dependent protein kinase catalytic subunit, anticorps protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a, anticorps PRKACA, anticorps Prkaca, anticorps kin-1, anticorps prkacaa

Sujet: CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC102831, MGC48865, PKACA
Protein Interaction Partner: MAPT, UBC, PALM2-AKAP2, NASP, MARCKS, CALU, CALR, TRMT10A, ARPC5L, AARSD1, UGDH, TPD52, SH3GL1, RPA2, SH3GLB1, UBQLN2, ARPC1A, ARPC2, ARPC3, ARPC5, smo, CYP3A4, GNA13, DYRK1B, TBXA2R, ITGA2B, GSK3B, PDE4D, EGFR, CALD1, BAD, HSP90AB1, HSP90AA1, C2orf88, CD
Protein Size: 343

Poids moléculaire: 40 kDa

ID gène: 5566

NCBI Accession: NM_207518, NP_997401

UniProt: A8K8B9

Pathways: Signalisation NF-kappaB, Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, Lipid Metabolism, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2