COL1A2 anticorps (Middle Region)

N° du produit ABIN2787684

Détail du produit anti-COL1A2 anticorps

Antigène: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Chévre, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL1A2 est non-conjugé

Application: Western Blotting (WB)

Séquence: PGSVGPAGPR GPAGPSGPAG KDGRTGHPGT VGPAGIRGPQ GHQGPAGPPG

Homologie: Cow: 100%, Dog: 93%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against COL1A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human COL1A2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1366 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur COL1A2

Antigène: COL1A2 (Collagen, Type I, alpha 2 (COL1A2))

Autre désignation: COL1A2 (COL1A2 Produits)

Synonymes: anticorps AA960264, anticorps AI325291, anticorps Col1a-2, anticorps Cola-2, anticorps Cola2, anticorps oim, anticorps OI4, anticorps Gas-6, anticorps alpha2(I), anticorps hm:zehn2357, anticorps wu:fa98d05, anticorps wu:fa99g10, anticorps wu:fb04c08, anticorps wu:fb11d06, anticorps zehn2357, anticorps coagulation factor II, thrombin, anticorps collagen, type I, alpha 2, anticorps collagen type I alpha 2 chain, anticorps collagen type I alpha 2 L homeolog, anticorps growth arrest specific 6, anticorps F2, anticorps Col1a2, anticorps col1a2.L, anticorps COL1A2, anticorps Gas6, anticorps col1a2

Sujet: COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: OI4
Protein Interaction Partner: UBQLN1, SGTA, PDGFB, PDGFA, COL1A1, PAN2, LIG4, MYOC, SHBG, UBC, MMP9, COL5A3, CD44, APP, P4HB, ITGA2B, TGFBI, LUM, BGN, VWF, ITGA2, SPARC, CD36, ITGB3, FN1, DCN, CD93,
Protein Size: 1366

Poids moléculaire: 150 kDa

ID gène: 1278

NCBI Accession: NM_000089, NP_000080

UniProt: P08123