PCSK2 anticorps (Middle Region)
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- Antigène Voir toutes PCSK2 Anticorps
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PCSK2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LASTFSNGRK RNPEAGVATT DLYGNCTLRH SGTSAAAPEA AGVFALALEA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PCSK2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PCSK2
- Top Product
- Discover our top product PCSK2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 638 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
- Autre désignation
- PCSK2 (PCSK2 Produits)
- Synonymes
- anticorps NEC 2, anticorps NEC-2, anticorps NEC2, anticorps PC2, anticorps SPC2, anticorps PCSK2, anticorps 6330411F23Rik, anticorps AI839700, anticorps Nec-2, anticorps Nec2, anticorps Phpp-2, anticorps pc2, anticorps nec2, anticorps spc2, anticorps pcsk2, anticorps pcsk2-A, anticorps proprotein convertase subtilisin/kexin type 2, anticorps proprotein convertase subtilisin/kexin type 2 L homeolog, anticorps PCSK2, anticorps pcsk2, anticorps Pcsk2, anticorps pcsk2.L
- Sujet
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This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: NEC2, PC2, SPC2, NEC 2, NEC-2
Protein Interaction Partner: PMCH, SCG5, IAPP, THRA,
Protein Size: 638 - Poids moléculaire
- 58 kDa
- ID gène
- 5126
- NCBI Accession
- NM_002594, NP_002585
- UniProt
- Q5REC2
- Pathways
- Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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