FPGS anticorps (Middle Region)

N° du produit ABIN2789500

Détail du produit anti-FPGS anticorps

Antigène: FPGS (Folylpolyglutamate Synthase (FPGS))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FPGS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: CWLQRQDRHG AGEPKASRPG LLWQLPLAPV FQPTSHMRLG LRNTEWPGRT

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FPGS. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 537 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FPGS (ABIN2789500)

Fukuda, Oguri, Kunii, Sone, Uemura, Takakuwa, Maeno, Kanemitsu, Ohkubo, Takemura, Ito, Niimi: "A folylpoly-γ-glutamate synthase single nucleotide polymorphism associated with response to pemetrexed treatment combined with platinum for non-small cell lung cancer." dans: Lung cancer (Amsterdam, Netherlands), Vol. 102, pp. 15-20, (2016) (PubMed).

Détails sur FPGS

Antigène: FPGS (Folylpolyglutamate Synthase (FPGS))

Autre désignation: FPGS (FPGS Produits)

Synonymes: anticorps zgc:63807, anticorps wu:fk49h03, anticorps wu:fk51d09, anticorps FPGS, anticorps fpgS, anticorps SCC88.25c, anticorps BA4689, anticorps AA408187, anticorps folylpolyglutamate synthase, anticorps dihydrofolate synthase, anticorps folylpolyglutamate synthase, mitochondrial, anticorps folylpolyglutamyl synthetase, anticorps fpgs, anticorps fpgS, anticorps FPGS, anticorps SCO2614, anticorps fgs, anticorps folC, anticorps CpipJ_CPIJ008043, anticorps Fpgs

Sujet: This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms.
Alias Symbols: -
Protein Interaction Partner: UBC,
Protein Size: 537

Poids moléculaire: 59 kDa

ID gène: 2356

NCBI Accession: NM_001018078, NP_001018088

UniProt: Q5JU19