FCGR3A anticorps (Middle Region)
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- Antigène Voir toutes FCGR3A Anticorps
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Souris, Cobaye, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FCGR3A est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DPIHLRCHSW KNTALHKVTY LQNGKGRKYF HHNSDFYIPK ATLKDSGSYF
- Homologie
- Guinea Pig: 79%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against FCGR3A. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product FCGR3A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 253 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
- Autre désignation
- FCGR3A (FCGR3A Produits)
- Synonymes
- anticorps CD16, anticorps CD16A, anticorps FCG3, anticorps FCGR3, anticorps FCGRIII, anticorps FCR-10, anticorps FCRIII, anticorps FCRIIIA, anticorps IGFR3, anticorps Fcgr4, anticorps Fc fragment of IgG receptor IIIa, anticorps FCGR3A, anticorps Fcgr3a
- Sujet
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This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
Protein Interaction Partner: SYK, ZBTB25, APP, IGHG1, GP6, SHC1, CD4, CD247, ZAP70, LCK, PTPRC, FCER1G, FCGR1A, CD38, APCS,
Protein Size: 253 - Poids moléculaire
- 27 kDa
- ID gène
- 2214
- NCBI Accession
- NM_001127596, NP_001121068
- UniProt
- P08637
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