TNFSF8 anticorps (N-Term)

N° du produit ABIN2789625

Détail du produit anti-TNFSF8 anticorps

Antigène: TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF8 est non-conjugé

Application: Western Blotting (WB)

Séquence: ATIMVLVVQR TDSIPNSPDN VPLKGGNCSE DLLCILKRAP FKKSWAYLQV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TNFSF8. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 234 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNFSF8

Antigène: TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))

Autre désignation: TNFSF8 (TNFSF8 Produits)

Synonymes: anticorps CD153, anticorps CD30LG, anticorps Cd30l, anticorps CD30L, anticorps TNFRSF8, anticorps TNFSF8, anticorps tumor necrosis factor (ligand) superfamily, member 8, anticorps TNF superfamily member 8, anticorps tumor necrosis factor superfamily member 8, anticorps Tnfsf8, anticorps TNFSF8

Sujet: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD153, CD30L, CD30LG, MGC138144
Protein Interaction Partner: TNFRSF8, ANG,
Protein Size: 234

Poids moléculaire: 26 kDa

ID gène: 944

NCBI Accession: NM_001244, NP_001235

UniProt: P32971