KDELR2 anticorps (Middle Region)
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- Antigène Voir toutes KDELR2 Anticorps
- KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KDELR2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PVGGLSFLVN HDFSPLEYSR ERSSVCQHKC QRPSPASVLQ GARTEFLPQQ
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against KDELR2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human KDELR2
- Top Product
- Discover our top product KDELR2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 186 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
- Autre désignation
- KDELR2 (KDELR2 Produits)
- Synonymes
- anticorps kdelr2, anticorps ELP-1, anticorps ERD2.2, anticorps 1110007A14Rik, anticorps kdelr1-a, anticorps KDEL endoplasmic reticulum protein retention receptor 2 L homeolog, anticorps KDEL endoplasmic reticulum protein retention receptor 2, anticorps KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, anticorps KDEL endoplasmic reticulum protein retention receptor 1 L homeolog, anticorps kdelr2.L, anticorps KDELR2, anticorps Kdelr2, anticorps kdelr1.L
- Sujet
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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83 % identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: ELP-1, ERD2.2
Protein Interaction Partner: UBC, ELAVL1, SERINC3,
Protein Size: 186 - Poids moléculaire
- 21 kDa
- ID gène
- 11014
- NCBI Accession
- NM_001100603, NP_001094073
- UniProt
- P33947
- Pathways
- Maintenance of Protein Location
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