ERK1 anticorps (N-Term)
Aperçu rapide pour ERK1 anticorps (N-Term) (ABIN2792053)
Antigène
Voir toutes ERK1 (MAPK3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- GGGGGEPRRT EGVGPGVPGE VEMVKGQPFD VGPRYTQLQY IGEGAYGMVS
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Homologie
- Human: 100%, Pig: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against MAPK3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MAPK3
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))
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Autre désignation
- MAPK3
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Sujet
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Protein Interaction Partner: MAPK1, DUSP4, STAR, RAF1, PTGDR, MAP2K1, NAB2, MYOG, DHPS, HDAC6, MAGED1, AMOT, FOXP2, CDC23, VPS52, L3MBTL3, TRIM54, DCP1A, UBC, TP53, PTGS2, RPS6KA2, MAPK3, PHF3, TEK, MBP, ELK1, CUEDC2, MAPKAPK2, GAB2, IRX2, ADAM15, VCP, ELK4, DAPK1, Rara, IQGAP1, TP53
Protein Size: 357 -
Poids moléculaire
- 39 kDa
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ID gène
- 5595
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Pathways
- Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins
Antigène
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