GCM2 anticorps (N-Term)
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- Antigène Voir toutes GCM2 Anticorps
- GCM2 (Glial Cells Missing Homolog 2 (GCM2))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Chien, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GCM2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- HSGYPVTNFW RLDGNAIFFQ AKGVHDHPRP ESKSETEARR SAIKRQMASF
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against GCM2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GCM2
- Top Product
- Discover our top product GCM2 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- GCM2 (Glial Cells Missing Homolog 2 (GCM2))
- Autre désignation
- GCM2 (GCM2 Produits)
- Synonymes
- anticorps GCMb, anticorps Gcm-2, anticorps gcm-2, anticorps GCMB, anticorps hGCMb, anticorps Gcm-rs1, anticorps Gcm1, anticorps Gcm1-rs2, anticorps glial cells missing homolog 2, anticorps glial cells missing homolog 2 (Drosophila), anticorps glial cells missing homolog 2 S homeolog, anticorps GCM2, anticorps gcm2, anticorps gcm2.S, anticorps Gcm2
- Sujet
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This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.
Alias Symbols: GCMB, hGCMb
Protein Interaction Partner: HSFY1, RBPMS, FHL3, CRX,
Protein Size: 506 - Poids moléculaire
- 57 kDa
- ID gène
- 9247
- NCBI Accession
- NM_004752, NP_004743
- UniProt
- O75603
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