RIPK1 anticorps (Middle Region)

N° du produit ABIN2792131

L’anticorps Lapin Polyclonal anti-RIPK1 a été validé pour WB. Il convient pour détecter RIPK1 dans des échantillons de Humain, Chien, Boeuf (Vache) et Cheval.

Aperçu rapide pour RIPK1 anticorps (Middle Region) (ABIN2792131)

Antigène: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Reactivité: Humain, Chien, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIPK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RIPK1 anticorps

Épitope: Middle Region

Séquence: RRRRVSHDPF AQQRPYENFQ NTEGKGTAYS SAASHGNAVH QPSGLTSQPQ

Homologie: Cow: 100%, Dog: 91%, Horse: 83%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RIPK1. It was validated on Western Blot using a cell lysate as a positive control.

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RIPK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 671 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RIPK1

Antigène: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Autre désignation: RIPK1

Sujet: FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.
Alias Symbols: RIP, RIP1
Protein Interaction Partner: RFFL, RIPK1, UBC, TRAF2, TRAF1, TNFRSF1A, TNF, OTUD1, YOD1, TRADD, IKBKG, FADD, CASP8, MAP3K7, BMH1, BIRC3, BIRC2, MAP3K8, OPTN, NUMBL, CFLAR, HSP90AA1, RIPK3, USP4, TNFAIP3, TNFSF10, LRRK2, TNFRSF10B, MAP3K3, HHV8GK18_gp80, DAB2IP, TNFRSF1B, IKBKB, CHUK,
Protein Size: 671

Poids moléculaire: 76 kDa

ID gène: 8737

NCBI Accession: NM_003804, NP_003795

UniProt: Q13546

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway