RIPK1 anticorps (Middle Region)

N° du produit ABIN2792131

L’anticorps anti-RIPK1 Polyclonal Lapin est utilisé pour la détection de RIPK1 dans des échantillons de Humain, Chien, Boeuf (Vache) et Cheval. Il a été validé pour WB.

Aperçu rapide pour RIPK1 anticorps (Middle Region) (ABIN2792131)

Antigène: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Reactivité: Humain, Chien, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIPK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RIPK1 anticorps

Épitope: Middle Region

Fonction: RIPK1 Antibody - middle region

Séquence: RRRRVSHDPF AQQRPYENFQ NTEGKGTAYS SAASHGNAVH QPSGLTSQPQ

Homologie: Cow: 100%, Dog: 91%, Horse: 83%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RIPK1. It was validated on Western Blot using a cell lysate as a positive control.

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RIPK1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RIPK1

Antigène: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Autre désignation: RIPK1

Sujet:

Background Information: FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.

Gene Name: Receptor (TNFRSF)-interacting serine-threonine kinase 1

Alternative Symbols: RIP, RIP1, AIEFL, IMD57, RIP-1

Protein Name: Receptor-interacting serine/threonine-protein kinase 1

Poids moléculaire: 76kDa

ID gène: 8737

NCBI Accession: NP_003795

UniProt: Q13546

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway