CHRNA3 anticorps (N-Term)

N° du produit ABIN2792258

Détail du produit anti-CHRNA3 anticorps

Antigène: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA3 est non-conjugé

Application: Western Blotting (WB)

Séquence: QEERLLADLM QNYDPNLRPA ERDSDVVNVS LKLTLTNLIS LNEREEALTT

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CHRNA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 505 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CHRNA3

Antigène: CHRNA3 (Cholinergic Receptor, Nicotinic, alpha 3 (Neuronal) (CHRNA3))

Autre désignation: CHRNA3 (CHRNA3 Produits)

Synonymes: anticorps LNCR2, anticorps NACHRA3, anticorps PAOD2, anticorps (a)3, anticorps A730007P14Rik, anticorps Acra-3, anticorps Acra3, anticorps cholinergic receptor nicotinic alpha 3 subunit, anticorps cholinergic receptor, nicotinic, alpha polypeptide 3, anticorps CHRNA3, anticorps Chrna3

Sujet: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[
Alias Symbols: ACHRG
Protein Interaction Partner: Ubqln1, CHRNB4,
Protein Size: 517

Poids moléculaire: 57 kDa

ID gène: 1146

NCBI Accession: NM_000743, NP_000734

UniProt: Q86U77

Pathways: Synaptic Membrane