SMAD6 anticorps (N-Term)
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- Antigène Voir toutes SMAD6 Anticorps
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
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Épitope
- N-Term
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Reactivité
- Humain, Boeuf (Vache), Porc, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SMAD6 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GAPRDASDPL AGAALEPAGG GRSREARSRL LLLEQELKTV TYSLLKRLKE
- Réactivité croisée
- Humain
- Homologie
- Cow: 85%, Dog: 91%, Human: 100%, Pig: 85%
- Attributs du produit
- This is a rabbit polyclonal antibody against SMAD6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD6
- Top Product
- Discover our top product SMAD6 Anticorps primaire
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- Indications d'application
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WB Suggested Anti-SMAD6 Antibody Titration: 0.2-1 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 496 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SMAD6 (SMAD, Mothers Against DPP Homolog 6 (SMAD6))
- Autre désignation
- SMAD6 (SMAD6 Produits)
- Synonymes
- anticorps madh6, anticorps madh7, anticorps Xsmad6, anticorps hst17432, anticorps AOVD2, anticorps HsT17432, anticorps MADH6, anticorps MADH7, anticorps Madh6, anticorps b2b390Clo, anticorps Smad6-like, anticorps smad6, anticorps wu:fb22g05, anticorps SMAD family member 6, anticorps SMAD family member 6a, anticorps smad6, anticorps SMAD6, anticorps Smad6, anticorps smad6a
- Sujet
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SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
Alias Symbols: HsT17432, MADH6, MADH7
Protein Interaction Partner: ITCH, SMURF2, BPIFA1, NEDD4L, WWP2, WWP1, USP15, USP11, PIGR, NASP, LYZ, KPNA2, CTBP2, CTBP1, UBC, ACVR1, UBE2O, BAMBI, STAMBP, ACTR1B, TGFBR1, MYD88, SMAD1, BMPR2, BMPR1B, BMPR1A, ACVR2B, ACVR1B, SMURF1, PELI1, CUL2, ELAVL1, SMAD5, RPS6KA5, TSC22D1, MAPK
Protein Size: 496 - Poids moléculaire
- 53 kDa
- ID gène
- 4091
- NCBI Accession
- NM_005585, NP_005576
- UniProt
- O43541
- Pathways
- Chromatin Binding
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