TFAP2A anticorps (C-Term)

N° du produit ABIN2792629

Détail du produit anti-TFAP2A anticorps

Antigène: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAP2A est non-conjugé

Application: Western Blotting (WB)

Séquence: NLISHGFGSP AVCAAVTALQ NYLTEALKAM DKMYLSNNPN SHTDNNAKSS

Réactivité croisée: Boeuf (Vache), Poulet, Humain, Souris, Porc, Rat (Rattus)

Homologie: Dog: 92%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TFAP2A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human TFAP2A

Information d'application

Indications d'application: WB Suggested Anti-TFAP2A Antibody Titration: 1.25 µg/mL
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 437 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TFAP2A

Antigène: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Autre désignation: AP-2 alpha / TFAP2A (TFAP2A Produits)

Synonymes: anticorps TFAP2A, anticorps Ap-2, anticorps AP-2, anticorps AP-2alpha, anticorps AP2TF, anticorps BOFS, anticorps TFAP2, anticorps ap2, anticorps xap2, anticorps XAP-2, anticorps ap2tf, anticorps tfap2, anticorps ap-2alpha, anticorps tfap2alpha, anticorps cb93, anticorps fb83f04, anticorps fc31a07, anticorps wu:fb83f04, anticorps wu:fc31a07, anticorps tfap2a-a, anticorps tcfap2a, anticorps ap2a, anticorps AP2alpha, anticorps Ap2, anticorps Ap2tf, anticorps Tcfap2a, anticorps AP2, anticorps transcription factor AP-2 alpha, anticorps transcription factor AP-2, anticorps tto transcription factor AP-2 alpha, anticorps to transcription factor AP-2 alpha L homeolog, anticorps to transcription factor AP-2 alpha S homeolog, anticorps Transcription factor AP-2 alpha, anticorps transcription factor AP-2, alpha, anticorps TFAP2A, anticorps LOC100302602, anticorps tfap2a, anticorps tfap2a.L, anticorps tfap2a.S, anticorps ap2a, anticorps Tfap2a

Sujet: TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM].
Alias Symbols: AP-2, BOFS, AP2TF, TFAP2, AP-2alpha
Protein Interaction Partner: MKRN3, GSTO2, KCTD15, SUMO1, HECW2, SP1, BAG3, RB1, UBC, DAB2, Fcho2, EPAS1, SRA1, EPS15, KCTD1, EPN1, SH3BP4, UBE2I, AURKA, BRCA1, DNMT3A, ELAVL1, SUMO4, SUMO2, NPM1, YY1, PPARG, EPN2, CITED4, LDLRAP1, CITED2, EP300, MAGI1, WWP2, WWP1, HIP1, CASP6, CASP3
Protein Size: 437

Poids moléculaire: 48 kDa

ID gène: 7020

NCBI Accession: NM_003220, NP_003211

UniProt: P05549

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism