TRIM22 anticorps (N-Term)

N° du produit ABIN2792634

Détail du produit anti-TRIM22 anticorps

Antigène: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM22 est non-conjugé

Application: Western Blotting (WB)

Séquence: LANIVERVKE VKMSPQEGQK RDVCEHHGKK LQIFCKEDGK VICWVCELSQ

Réactivité croisée: Humain

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TRIM22. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM22

Information d'application

Indications d'application: WB Suggested Anti-TRIM22 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 498 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIM22

Antigène: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Autre désignation: TRIM22 / RNF94 (TRIM22 Produits)

Synonymes: anticorps GPSTAF50, anticorps RNF94, anticorps STAF50, anticorps tripartite motif containing 22, anticorps TRIM22

Sujet: TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPSTAF50, RNF94, STAF50
Protein Interaction Partner: EIF4E, UBC, TAB2, CASK, CIC, TRIM22, USP7, RERE, ZZZ3, TAF7, CREB1,
Protein Size: 498

Poids moléculaire: 57 kDa

ID gène: 10346

NCBI Accession: NM_006074, NP_006065

UniProt: Q8IYM9