C-JUN anticorps (N-Term)

N° du produit ABIN2792650

L’anticorps Lapin Polyclonal anti-C-JUN a été validé pour WB, IHC et ChIP. Il convient pour détecter C-JUN dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Chien et Mouton. Il y a 1 publication disponible.

Aperçu rapide pour C-JUN anticorps (N-Term) (ABIN2792650)

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Chien, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C-JUN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-C-JUN anticorps

Épitope: N-Term

Séquence: TAKMETTFYD DALNASFLPS ESGPYGYSNP KILKQSMTLN LADPVGSLKP

Réactivité croisée: Boeuf (Vache), Chien, Humain, Souris, Porc, Rat (Rattus)

Homologie: Cow: 92%, Dog: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 92%, Sheep: 92%

Attributs du produit: This is a rabbit polyclonal antibody against JUN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human JUN

Information d'application

Indications d'application: WB Suggested Anti-JUN Antibody Titration: 0.2-1 µg/mL
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 331 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-C-JUN (ABIN2792650)

Russo, Pinsino, Costa, Bonaventura, Matranga, Zito: "The newly characterized Pl-jun is specifically expressed in skeletogenic cells of the Paracentrotus lividus sea urchin embryo." dans: The FEBS journal, Vol. 281, Issue 17, pp. 3828-43, (2014) (PubMed).

Détails sur C-JUN

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Autre désignation: AP-1 / c-Jun

Sujet: JUN gene is the putative transforming gene of avian sarcoma virus 17. I JUN is highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. JUN gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AP1, c-Jun, AP-1
Protein Interaction Partner: PPP3CA, SP1, HDAC1, GSK3B, FOS, ABL1, MAPK8, RFWD2, CORO7, EP300, STRN4, MAPRE3, CREB3, PRRC2A, MDM2, SMAD2, HSP90AA1, HSPA8, ATF2, APP, APLP2, GOPC, BBS7, ETS1, CREBBP, CASP9, UBC, NCOR1, EPAS1, DDIT3, BATF2, BATF3, BATF, FOSL1, SMARCD3, CEBPG, CEBPE, AT
Protein Size: 331

Poids moléculaire: 36 kDa

ID gène: 3725

NCBI Accession: NM_002228, NP_002219

UniProt: P05412

Pathways: Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins