TCEB1 anticorps (Middle Region)
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- Antigène Voir toutes TCEB1 Anticorps
- TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
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Épitope
- Middle Region
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Reactivité
- Humain, Chien, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TCEB1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- AENETNEVNF REIPSHVLSK VCMYFTYKVR YTNSSTEIPE FPIAPEIALE
- Réactivité croisée
- Boeuf (Vache), Chien, Poulet, Mouche des fruits (Drosophila melanogaster), Humain, Souris, Rat (Rattus)
- Homologie
- Dog: 100%, Human: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against TCEB1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TCEB1
- Top Product
- Discover our top product TCEB1 Anticorps primaire
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- Indications d'application
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WB Suggested Anti-TCEB1 Antibody Titration: 1.0 µg/mL
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 112 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))
- Autre désignation
- TCEB1 (TCEB1 Produits)
- Synonymes
- anticorps 2610043E24Rik, anticorps 2610301I15Rik, anticorps AA407206, anticorps AI987979, anticorps AW049146, anticorps SIII, anticorps eloC, anticorps TCEB1, anticorps fb09f09, anticorps wu:fb09f09, anticorps zgc:111990, anticorps zgc:92635, anticorps elongin C, anticorps elongin C L homeolog, anticorps transcription elongation factor B (SIII), polypeptide 1b, anticorps Eloc, anticorps eloc.L, anticorps ELOC, anticorps tceb1b
- Sujet
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TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alias Symbols: SIII, eloC
Protein Interaction Partner: UBC, TCEB2, FUS, vif, METTL21C, SOCS4, CUL5, PRAME, POP1, MDM2, VHL, ASB18, ASB12, ASB14, ASB15, ASB9, ASB8, ASB7, ASB5, ASB10, ASB16, ASB13, ASB1, ASB3, APEX1, CUL2, Zswim8, ASB2, CPTP, CBX5, MRAS, JTB, RCAN2, SOCS1, CUL3, WNT7B, NEDD8, HIF1A, EFNB3, CYP
Protein Size: 112 - Poids moléculaire
- 12 kDa
- ID gène
- 6921
- NCBI Accession
- NM_005648, NP_005639
- UniProt
- Q15369
- Pathways
- SARS-CoV-2 Protein Interactome
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