Src anticorps (N-Term)
Aperçu rapide pour Src anticorps (N-Term) (ABIN2793858)
Antigène
Voir toutes Src AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 24-52, N-Term
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Fonction
- Rabbit Anti-Human SRC (N-term) Antibody
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Immunogène
- This SRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human SRC.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot, Immunohistochemistry, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:2000, IHC: 1:50, FC: 1:50, IF: 1:50SRC Antibody (N-term) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.500 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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Autre désignation
- SRC
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Sujet
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Target Description: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Gene Symbol: SRC
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Poids moléculaire
- 59835 Da
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ID gène
- 6714
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UniProt
- P12931
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Pathways
- Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Antigène
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