TPX2 anticorps (AA 350-382)

N° du produit ABIN2796197

Détail du produit anti-TPX2 anticorps

Antigène: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Épitope: AA 350-382

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPX2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: Rabbit Anti-Human P100 Antibody

Immunogène: This P100 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-382 amino acids from human P100.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100The anti-p100 Pab is used in Western blot to detect p100 in placenta lysate.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur TPX2

Antigène: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Autre désignation: P100 (TPX2 Produits)

Synonymes: anticorps C20orf1, anticorps C20orf2, anticorps DIL-2, anticorps DIL2, anticorps FLS353, anticorps GD:C20orf1, anticorps HCA519, anticorps HCTP4, anticorps REPP86, anticorps p100, anticorps 2610005B21Rik, anticorps TPX2, anticorps dil-2, anticorps dil2, anticorps hctp4, anticorps repp86, anticorps tpx2, anticorps TPX2, microtubule nucleation factor, anticorps TPX2, microtubule-associated, anticorps TPX2, microtubule-associated, homolog (Xenopus laevis), anticorps TPX2, microtubule-associated S homeolog, anticorps TPX2, microtubule-associated L homeolog, anticorps TPX2, anticorps Tpx2, anticorps tpx2.S, anticorps tpx2.L

Sujet:

Target Description: The nuclear protein p100 is a proliferation-associated protein whose expression is restricted to cell cycle phases S, G2, and M. Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. The full-length cDNA encodes a 747-amino acid protein with a putative ATP/GTP-binding site motif. RT-PCR analysis demonstrated strong expression of in lung carcinoma cell lines but not in normal lung tissues. Expression was also found in adult placenta, skeletal muscle, thymus, testis, and small intestine and in fetal brain, liver, and kidney. P100 is also correlated to cancer prognosis.

Gene Symbol: TPX2

Poids moléculaire: 85653 Da

ID gène: 22974

UniProt: Q9ULW0