ADAM17 anticorps (C-Term)

N° du produit ABIN2798820

Cet anticorps anti-ADAM17 est un anticorps Lapin Polyclonal détectant ADAM17 dans WB. Adapté pour Humain.

Aperçu rapide pour ADAM17 anticorps (C-Term) (ABIN2798820)

Antigène: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM17 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ADAM17 anticorps

Épitope: AA 794-823, C-Term

Fonction: Rabbit Anti-Human ADAM17 (C-term) Antibody

Immunogène: This ADAM17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 794-823 amino acids from the C-terminal region of human ADAM17.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of ADAM17 Antibody (N-term) in Jurkat cell line lysates (35 μg/lane). ADAM17(arrow) was detected using the purified Pab.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur ADAM17

Antigène: ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))

Autre désignation: ADAM17

Sujet:

Target Description: ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.

Gene Symbol: ADAM17

Poids moléculaire: 93021 Da

ID gène: 6868

UniProt: P78536

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus