SHC3 anticorps

N° du produit ABIN1944948

Détail du produit anti-SHC3 anticorps

Antigène: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHC3 est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG

Information d'application

Indications d'application: WB - 1:1000

Restrictions: For Research Use only

Stockage

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Références pour anticorps anti-SHC3 (ABIN1944948)

Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: "DNA sequence and analysis of human chromosome 9. ..." dans: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).

Liu, Meakin: "ShcB and ShcC activation by the Trk family of receptor tyrosine kinases." dans: The Journal of biological chemistry, Vol. 277, Issue 29, pp. 26046-56, (2002) (PubMed).

Nakamura, Sanokawa, Sasaki, Ayusawa, Oishi, Mori: "N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway." dans: Oncogene, Vol. 13, Issue 6, pp. 1111-21, (1996) (PubMed).

Pelicci, Dente, De Giuseppe, Verducci-Galletti, Giuli, Mele, Vetriani, Giorgio, Pandolfi, Cesareni, Pelicci: "A family of Shc related proteins with conserved PTB, CH1 and SH2 regions." dans: Oncogene, Vol. 13, Issue 3, pp. 633-41, (1996) (PubMed).

Détails sur SHC3

Antigène: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Autre désignation: SHC3 (SHC3 Produits)

Synonymes: anticorps N-Shc, anticorps NSHC, anticorps RAI, anticorps SHCC, anticorps ShcC, anticorps Rai, anticorps SHC adaptor protein 3, anticorps src homology 2 domain-containing transforming protein C3, anticorps SHC3, anticorps Shc3

Sujet: Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Synonyms: SHC-transforming protein 3, Neuronal Shc, N-Shc, Protein Rai, SHC-transforming protein C, Src homology 2 domain-containing-transforming protein C3, SH2 domain protein C3, SHC3, NSHC, SHCC

Poids moléculaire: 64056 Da

ID gène: 53358

UniProt: Q92529

Pathways: Signalisation RTK, EGFR Signaling Pathway, Neurotrophin Signaling Pathway