Complement Factor H anticorps

N° du produit ABIN2854706

Détail du produit anti-Complement Factor H anticorps

Antigène: Complement Factor H (CFH)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement Factor H est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain

Attributs du produit: Rabbit Polyclonal antibody to Factor H (complement factor H)
Factor H antibody [N3C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Factor H. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: human plasma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Complement Factor H

Antigène: Complement Factor H (CFH)

Autre désignation: complement factor H (CFH Produits)

Synonymes: anticorps AHUS1, anticorps AMBP1, anticorps ARMD4, anticorps ARMS1, anticorps CFHL3, anticorps FH, anticorps FHL1, anticorps HF, anticorps HF1, anticorps HF2, anticorps HUS, anticorps Mud-1, anticorps NOM, anticorps Sas-1, anticorps Sas1, anticorps Fh, anticorps CFH, anticorps im:7147412, anticorps si:ch211-207o17.2, anticorps fH, anticorps armd4, anticorps arms1, anticorps cfh, anticorps cfhl3, anticorps fhl1, anticorps hf1, anticorps hf2, anticorps hus, anticorps complement factor H, anticorps complement component factor h, anticorps complement factor H-related protein 5, anticorps complement factor H L homeolog, anticorps CFH, anticorps Cfh, anticorps cfh, anticorps LOC100399888, anticorps LOC100733902, anticorps cfh.L

Sujet: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Cellular Localization: Secreted

Poids moléculaire: 139 kDa

ID gène: 3075

UniProt: P08603

Pathways: Système du Complément, Cellular Response to Molecule of Bacterial Origin