AP2B1 anticorps (Internal Region)

N° du produit ABIN2855154

Détail du produit anti-AP2B1 anticorps

Antigène: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AP2B1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Boeuf (Vache)

Réactivité croisée (Details): Bovine (100 %)

Attributs du produit: Rabbit polyclonal antibody to beta-Adaptin (adaptor-related protein complex 1, beta 1 subunit)
beta-Adaptin antibody [N3C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human beta-Adaptin. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.55 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur AP2B1

Antigène: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Autre désignation: beta-Adaptin (AP2B1 Produits)

Synonymes: anticorps 5-HT(2B), anticorps 5-HT2B, anticorps ADTB2, anticorps AP105B, anticorps AP2-BETA, anticorps CLAPB1, anticorps 1300012O03Rik, anticorps AI788979, anticorps fa16e07, anticorps wu:fa16c06, anticorps wu:fa16e07, anticorps wu:fc18c08, anticorps zgc:55659, anticorps 5-hydroxytryptamine receptor 2B, anticorps adaptor related protein complex 2 beta 1 subunit, anticorps adaptor-related protein complex 2, beta 1 subunit, anticorps adaptor related protein complex 2 beta 1 subunit L homeolog, anticorps HTR2B, anticorps AP2B1, anticorps Ap2b1, anticorps ap2b1, anticorps ap2b1.L

Sujet: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Two transcript variants encoding different isoforms have been found for this gene, and variants utilizing alternative polyadenylation signals exist.

Cellular Localization: Golgi apparatus , Cytoplasmic vesicle , clathrin-coated vesicle membrane

Poids moléculaire: 105 kDa

ID gène: 162

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation