RICTOR anticorps (C-Term)

N° du produit ABIN2855866

Détail du produit anti-RICTOR anticorps

Antigène: RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RICTOR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to RICTOR
RICTOR antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RICTOR. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A431

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-RICTOR (ABIN2855866)

Liu, Zhang, Li, Cao, Wan, Xi, Tan, Wang, Yang, Feng, Ye, Chen, Wu, Xi, Wang, Zhou, Feng, Ma, Gao: "C/EBPβ enhances platinum resistance of ovarian cancer cells by reprogramming H3K79 methylation." dans: Nature communications, Vol. 9, Issue 1, pp. 1739, (2018) (PubMed).

Détails sur RICTOR

Antigène: RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))

Autre désignation: RPTOR independent companion of MTOR complex 2 (RICTOR Produits)

Synonymes: anticorps PIA, anticorps mAVO3, anticorps 4921505C17Rik, anticorps 6030405M08Rik, anticorps AVO3, anticorps AW492497, anticorps D530039E11Rik, anticorps Fyb, anticorps RPTOR independent companion of MTOR complex 2, anticorps RPTOR independent companion of MTOR, complex 2, anticorps RICTOR, anticorps Rictor

Sujet: RICTOR and MTOR (FRAP1, MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM]

Poids moléculaire: 192 kDa

ID gène: 253260

UniProt: Q6R327

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events