WNT1 anticorps (Center)
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- Antigène Voir toutes WNT1 Anticorps
- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
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Épitope
- Center
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WNT1 est non-conjugé
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Application
- Western Blotting (WB)
- Réactivité croisée
- Souris, Rat (Rattus)
- Réactivité croisée (Details)
- Mouse (100 %), Rat (100 %)
- Attributs du produit
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Rabbit Polyclonal antibody to WNT1 (proto-oncogene Wnt-1)
Wnt1 antibody - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human Wnt1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product WNT1 Anticorps primaire
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- Indications d'application
- Suggested dilution Reference Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:1000-1:10000*
- Commentaires
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Positive Control: WNT1 transfected 293T lysate
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.82 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
- Autre désignation
- Wnt1 (WNT1 Produits)
- Synonymes
- anticorps Xint-1, anticorps Xwnt1, anticorps int-1, anticorps int1, anticorps wnt-1, anticorps wnt1-a, anticorps Int-1, anticorps Wnt-1, anticorps sw, anticorps swaying, anticorps BMND16, anticorps INT1, anticorps OI15, anticorps Int1, anticorps WNT-1, anticorps sb:eu647, anticorps zgc:194464, anticorps zgc:194478, anticorps WNT1, anticorps Wnt family member 1, anticorps Wnt family member 1 L homeolog, anticorps wingless-type MMTV integration site family, member 1, anticorps WNT1, anticorps wnt1.L, anticorps Wnt1, anticorps wnt1
- Sujet
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98 % identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
Cellular Localization: Secreted , extracellular space , extracellular matrix - Poids moléculaire
- 41 kDa
- ID gène
- 7471
- Pathways
- Signalisation WNT, Dopaminergic Neurogenesis
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