Angiotensin II Type-1 Receptor anticorps

N° du produit ABIN289368

Détail du produit anti-Angiotensin II Type-1 Receptor anticorps

Antigène: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Reactivité: Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiotensin II Type-1 Receptor est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificité: The 10 aa peptide is 100%, identical in Mouse, Ovine rat, human, Pig,and rabbit.

Réactivité croisée (Details): This 10 AA immunogenic peptide is 100 % identical in mouse, rat, human, ovine, pig, dog, chimpanzee and chicken. The sequence is the same in all AT II receptor isoforms (Type 1a, 1b, and 1c).

Purification: Affinity chromatography purified

Immunogène: AGTR1 antibody was raised in chicken using 10-aa peptide from rat AT-II type 1 as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1:10,000-1:100,000, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in PBS to a concentration of 1 mg/mL

Concentration: Lot specific

Buffer: Lyophilized from PBS with 0.1 % BSA.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Références pour anticorps anti-Angiotensin II Type-1 Receptor (ABIN289368)

Walch, Carreño, Cunningham: "Intracerebroventricular losartan infusion modulates angiotensin II type 1 receptor expression in the subfornical organ and drinking behaviour in bile-duct-ligated rats." dans: Experimental physiology, Vol. 98, Issue 4, pp. 922-33, (2013) (PubMed).

Détails sur Angiotensin II Type-1 Receptor

Antigène: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Autre désignation: AGTR1 (AGTR1 Produits)

Synonymes: anticorps AG2S, anticorps AGTR1A, anticorps AGTR1B, anticorps AT1, anticorps AT1AR, anticorps AT1B, anticorps AT1BR, anticorps AT1R, anticorps AT2R1, anticorps AT2R1A, anticorps AT2R1B, anticorps HAT1R, anticorps 1810074K20Rik, anticorps AI551199, anticorps AT1a, anticorps Agtr-1a, anticorps Agtr1, anticorps Angtr-1a, anticorps AT1A, anticorps XAT-1, anticorps agtr1-A, anticorps agtr1.2, anticorps AT1-R, anticorps at1, anticorps AGTR1, anticorps Agtr-1b, anticorps Angtr-1b, anticorps agtr1, anticorps agtr1-a, anticorps agtr1-b, anticorps xAT, anticorps angiotensin II receptor type 1, anticorps angiotensin II receptor, type 1a, anticorps angiotensin II receptor type 1 S homeolog, anticorps uncharacterized AGTR1, anticorps angiotensin II receptor, type 1b, anticorps angiotensin II receptor type 1 L homeolog, anticorps AGTR1, anticorps Agtr1a, anticorps agtr1.S, anticorps Agtr1, anticorps Agtr1b, anticorps agtr1.L

Sujet: Angiotensin II receptor, type 1 or AT1 receptor is an angiotensin receptor. It has vasopressor effects and regulates aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. Angiotensin II receptor antagonists are drugs indicated for hypertension, diabetic nephropathy and congestive heart failure.

Pathways: Signalistation JAK/STAT, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour