Aurora A anticorps

N° du produit ABIN289985

Détail du produit anti-Aurora A anticorps

Antigène: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: This antibody was purified from rabbit serum by affinity chromatography.

Immunogène: GST-Human Aurora-A fusion Protein

Information d'application

Indications d'application: Working dilution For western blotting , 0.5-2 ug/mlFor Immunohistochemistry , 1-2ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur Aurora A

Antigène: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Autre désignation: Aurora-A (AURKA Produits)

Synonymes: anticorps AIK, anticorps ARK1, anticorps AURA, anticorps AURORA2, anticorps BTAK, anticorps PPP1R47, anticorps STK15, anticorps STK6, anticorps STK7, anticorps AIRK1, anticorps AU019385, anticorps AW539821, anticorps Ark1, anticorps Aurora-A, anticorps Ayk1, anticorps IAK, anticorps IAK1, anticorps Stk6, anticorps 87A7-9/2, anticorps Aur-A, anticorps AurA, anticorps CG3068, anticorps Dmel\\CG3068, anticorps aur-A, anticorps aurA, anticorps ck10, anticorps ck[10], anticorps l(3)87Ac, anticorps l(3)ck10, anticorps ARK-1, anticorps Eg2, anticorps aik, anticorps ark1, anticorps aur-a, anticorps aura, anticorps aurka-a, anticorps aurora2, anticorps btak, anticorps stk15, anticorps stk6, anticorps stk7, anticorps pEg2, anticorps wu:fb37c10, anticorps wu:fc02c02, anticorps zgc:100912, anticorps AURKA, anticorps aurka, anticorps aurora kinase A, anticorps aurora A, anticorps aurora kinase A L homeolog, anticorps hypothetical protein, anticorps aurora kinase A S homeolog, anticorps AURKA, anticorps Aurka, anticorps aurA, anticorps aurka.L, anticorps aurka, anticorps Aurora-A, anticorps aurka.S

Sujet: Aurora-A (Aurora-A/STK-15/Aik) encoding a centrosome-associated kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. So that, Aurora-A is a potentialoncogene. Aurora family have been identified three types (Aurora-A, B, C) which has high homologydomain in C terminal region. Aurora family is indispensable kinase that regulate the structure and functionof centrosomes and spindle. Aurora-A could be one of targeting molecule of anti-cancer therapy.This antibody was established from the purified serum of the immunized rabbit with N terminal region ofAurora-A and did not show any cross- reactivity to Aurora-B and Aurora-C. This antibody is useful forwestern blotting and immunohistochemistry.

Pathways: Cycle Cellulaire, Asymmetric Protein Localization