ADRB3 anticorps

N° du produit ABIN290046

Détail du produit anti-ADRB3 anticorps

Antigène: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRB3 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the C-terminal domain of Human beta3-AR, and purified by peptide affinity chromatography.

Immunogène: Partial peptide of Human beta3-AR

Information d'application

Indications d'application: Working dilution For Western blotting: 5.0ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur ADRB3

Antigène: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Autre désignation: beta3-AR (ADRB3 Produits)

Synonymes: anticorps BETA3AR, anticorps Adrb-3, anticorps ADRB, anticorps BAR3, anticorps B3AR, anticorps GPCR, anticorps im:7154935, anticorps si:ch211-215f19.1, anticorps zgc:194843, anticorps zgc:194852, anticorps adrenoceptor beta 3, anticorps adrenergic receptor, beta 3, anticorps adrenoceptor beta 3a, anticorps adrenoceptor beta 3b, anticorps ADRB3, anticorps Adrb3, anticorps adrb3a, anticorps adrb3b

Sujet: The neurotransmitter/hormone adrenaline (epinephrine, adrenalin) plays a central role in the mammalianstress response, increasing heart rate, raising blood pressure, and increasing blood glucose levels upon enteringthe blood stream.Adrenaline is secreted primarily by the adrenal medulla. Adrenaline activates both alpha-adrenergic receptors and beta-adrenergic receptors. Three subtypes of beta adrenergic receptors are known, beta1, beta2, beta3, expressed primarily inheart, respiratory tissue, and adipose tissue, respectively. Beta3-receptors are particularly abundant in brown adipocytes and play important roles in lipolysis andtheremoregulation. (Ref.1, Ref.2) Recently this receptor has received attention from researchers intereseted in type 2diabetes mellitus and obesity. It is also being considered as a therapertic target for heart failure (Ref.3).

Pathways: cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation