TRPA1 anticorps

N° du produit ABIN290051

Détail du produit anti-TRPA1 anticorps

Antigène: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPA1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purification: This antibody was established from the serum of a rabbit immunized with the partial peptide corresponding to amino acid 12-24 of mouse TRPA1, and purified by peptideaffinity chromatography.

Immunogène: Partial peptide of Mouse TRPA1

Information d'application

Indications d'application: Working dilution For Western blotting 1.6 ug/ml. For Immunoprecipitation 1.6 ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur TRPA1

Antigène: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Autre désignation: TRPA1 (TRPA1 Produits)

Synonymes: anticorps trpa1, anticorps ANKTM1, anticorps Anktm1, anticorps CG5751, anticorps CG5761, anticorps CT18073, anticorps DmTRPA1, anticorps Dmel\\CG5751, anticorps TRPA, anticorps TRPA1, anticorps TrpA, anticorps dANKTM1, anticorps dTRPA, anticorps dTRPA1, anticorps dTrpA, anticorps dTrpA1, anticorps dtrpA1, anticorps trpA1, anticorps GLEAN_02449, anticorps FEPS, anticorps transient receptor potential cation channel, subfamily A, member 1a, anticorps Transient receptor potential cation channel A1, anticorps transient receptor potential cation channel subfamily A member 1, anticorps transient receptor potential A1, anticorps tryptophan synthase subunit alpha 1, anticorps transient receptor potential cation channel, subfamily A, member 1, anticorps TRPA cation channel homolog, anticorps trpa1a, anticorps TrpA1, anticorps TRPA1, anticorps LOC658860, anticorps LOC694623, anticorps trpA1, anticorps trpa1, anticorps Trpa1, anticorps trpa-1

Sujet: Mammals feel a wide range of temperature spanning from cold to heat with specialized neurons in theperipheral nervous system. With this range, temperatures over about 43 degrees C and below about 15 degrees Cevoke not only a thermal sensation, but also a feeling of pain.Nine thermosensitive ion channels have been reported, all of which belong to TRP (transient receptorpotential) superfamily. They are expressed in sensory tissues, such as nociceptors and skin. Among them, TRPA1(TRP cation channel, subfamily A, member 1) has been identified as cold-sensitive ion channel. TRPA1 isactivated at approximately 17 degrees C, a temperature that is reported as painfully cold by humans.In addition to noxious cold, TRPA1 is activated pungent ingredients present in mustard, garlic, ginger, clove,wintergreen and cinnamon all and found in a subset of nociceptive sensory neurons where it is coexpressed withTRPV1/VR1 (capsaicin/heat receptor). Moreover, TRPA1 has been proposed to be a component of themechanosensitive transduction channel of vertebrate hair cells.This antibody will be very useful to research the nocifensive (thermosensitive and mechanosensitive) responseto pain.