TNK2 anticorps (AA 70-385)

N° du produit ABIN1683072

Détail du produit anti-TNK2 anticorps

Antigène: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Épitope: AA 70-385

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNK2 est non-conjugé

Application: Western Blotting (WB)

Séquence: TGWLLELLSE VQLQQYFLRL RDDLNVTRLS HFEYVKNEDL EKIGMGRPGQ RRLWEAVKRR KALCKRKSWM SKVFSGKRLE AEFPPHHSQS TFRKTSPAPG GPAGEGPLQS LTCLIGEKDL RLLEKLGDGS FGVVRRGEWD APSGKTVSVA VKCLKPDVLS QPEAMDDFIR EVNAMHSLDH RNLIRLYGVV LTPPMKMVTE LAPLGSLLDR LRKHQGHFLL GTLSRYAVQV AEGMGYLESK RFIHRDLAAR NLLLATRDLV KIGDFGLMRA LPQNDDHYVM QEHRKVPFAW CAPESLKTRT FSHASDTWMF GVTLWE

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 70-385 of human TNK2 (NP_001010938.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-TNK2 (ABIN1683072)

Hu, Xu, Yin, Zhang, Lu, Wu, Xue, Ho, Gao, Zhao, Zhang: "Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded." dans: Cell discovery, Vol. 2, pp. 15047, (2016) (PubMed).

Détails sur TNK2

Antigène: TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Autre désignation: TNK2 (TNK2 Produits)

Synonymes: anticorps ACK, anticorps ACK-1, anticorps ACK1, anticorps p21cdc42Hs, anticorps AW552477, anticorps Ack, anticorps Cdgip, anticorps Pyk1, anticorps ack1, anticorps ackb, anticorps tnk2, anticorps tnk2b, anticorps wu:fj16g04, anticorps zgc:154019, anticorps tyrosine kinase non receptor 2, anticorps tyrosine kinase, non-receptor, 2, anticorps tyrosine kinase, non-receptor, 1, anticorps TNK2, anticorps Tnk2, anticorps tnk1

Sujet: This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.,TNK2,ACK,ACK-1,ACK1,p21cdc42Hs,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,EGF,TNK2

Poids moléculaire: 60 kDa/114 kDa/119 kDa

ID gène: 10188

UniProt: Q07912