CHEK1 anticorps (pSer280)
Aperçu rapide pour CHEK1 anticorps (pSer280) (ABIN3019446)
Antigène
Voir toutes CHEK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- pSer280
-
Séquence
- VTSGG
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Phosphorylated Antibodies
-
Purification
- Affinity purification
-
Immunogène
- A synthetic phosphorylated peptide around S280 of human Chk1 (NP_001265.2).
-
Isotype
- IgG
-
-
anti-Checkpoint Kinase 1 (CHEK1) (pSer345) antibody
CHEK1 Reactivité: Humain WB, IF, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibodyCHEK1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibodyCHEK1 Reactivité: Humain WB, IHC (p), DB Hôte: Lapin Polyclonal RB7845-RB18425 unconjugated
anti-Checkpoint Kinase 1 (CHEK1) antibodyCHEK1 Reactivité: Humain, Souris WB, ELISA Hôte: Souris Monoclonal 2G1D5 unconjugated
anti-Checkpoint Kinase 1 (CHEK1) antibodyCHEK1 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Monoclonal 2F2 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) antibodyKD Validated CHEK1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB2890 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibodyKD Validated CHEK1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB3390 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) antibodyKD Validated CHEK1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB2815 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibodyCHEK1 Reactivité: Humain IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (AA 361-476) antibodyCHEK1 Reactivité: Humain ELISA, IF Hôte: Souris Monoclonal 2G3 unconjugated
-
-
Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
-
Autre désignation
- CHEK1
-
Sujet
- The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.,CHEK1,CHK1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,G1/S Checkpoint,G2/M DNA Damage Checkpoint,Protein phosphorylation,CHEK1
-
Poids moléculaire
- 43 kDa/50 kDa/54 kDa
-
ID gène
- 1111
-
UniProt
- O14757
-
Pathways
- Signalisation p53, Apoptose, Cycle Cellulaire, Réparation de l'ADN
Antigène
-
