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Retinoblastoma 1 anticorps (pSer780)

Name: Retinoblastoma 1 anticorps (pSer780)
Brand: antibodies-online
SKU: ABIN3020472
Price: 879.42 EUR
Availability: InStock

RB1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated

Western blot analysis of extracts from 3T3 cells, using Phospho-RB1-S780 antibody. (Retinoblastoma 1 anticorps (pSer780))

Immunohistochemistry of paraffin-embedded rat brain using Phospho-RB-S780 Rabbit pAb (ABIN3020471, ABIN3020472, ABIN3020473 and ABIN1681996) at dilution of 1:100 (40x lens). (Retinoblastoma 1 anticorps (pSer780))

IHC

Immunohistochemistry (IHC) image for anti-Retinoblastoma 1 (RB1) (pSer780) antibody (ABIN3020472) (Retinoblastoma 1 anticorps (pSer780))

IHC

Immunofluorescence staining of methanol-fixed Hela cells, using Phospho-RB1-S780 antibody. (Retinoblastoma 1 anticorps (pSer780))

Western blot analysis of extracts of NIH/3T3 cells, using Phospho-RB-S780 antibody (ABIN3020471, ABIN3020472, ABIN3020473 and ABIN1681996) at dilution. (Retinoblastoma 1 anticorps (pSer780))

Immunohistochemistry of paraffin-embedded mouse brain using Phospho-RB-S780 Rabbit pAb (ABIN3020471, ABIN3020472, ABIN3020473 and ABIN1681996) at dilution of 1:100 (40x lens). (Retinoblastoma 1 anticorps (pSer780))

IHC

Immunohistochemistry of paraffin-embedded human colon using Phospho-RB-S780 Rabbit pAb (ABIN3020471, ABIN3020472, ABIN3020473 and ABIN1681996) at dilution of 1:100 (40x lens). (Retinoblastoma 1 anticorps (pSer780))

IHC

7 images

N° du produit ABIN3020472

Fiche de données

Antigène Voir toutes Retinoblastoma 1 (RB1) Anticorps

Retinoblastoma 1 (RB1)
Épitope
36

34

29

25

24

22

20

15

11

10

10

7

6

6

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer780
Reactivité
301

120

101

6

4

4

4

3

3

3

2

1

1

1
Humain
Hôte
252

52
Lapin
Anticorps secondaires appropriés
Clonalité
238

66
Polyclonal
Conjugué
153

19

17

16

11

11

8

8

6

6

6

6

6

6

6

6

6

1

1

1

1

1

1

1
Cet anticorp Retinoblastoma 1 est non-conjugé
Application
227

132

114

80

79

42

42

36

28

20

19

9

8

6

6

6

4

2

1
Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée

Humain, Souris, Rat

Attributs du produit

Phosphorylated Antibodies

Immunogène

A phospho specific peptide corresponding to residues surrounding S780 of human RB

Isotype

IgG

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anti-Retinoblastoma 1 (RB1) (pSer780) antibody
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anti-Retinoblastoma 1 (RB1) (pSer780) antibody
RB1 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions

For Research Use only
Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Avoid freeze / thaw cycles.
Antigène

Retinoblastoma 1 (RB1)

Autre désignation

RB1 (RB1 Produits)

Synonymes

anticorps OSRC, anticorps RB, anticorps p105-Rb, anticorps pRb, anticorps pp110, anticorps Rb, anticorps Rb-1, anticorps P105-RB, anticorps PP110, anticorps RB11, anticorps zgc:154147, anticorps RB transcriptional corepressor 1, anticorps RB transcriptional corepressor like 1, anticorps retinoblastoma 1, anticorps RB1, anticorps RBL1, anticorps Rb1, anticorps rb1

Sujet

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.,OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,Protein phosphorylation,RB1

Poids moléculaire

106 kDa

ID gène

5925

UniProt

P06400

Pathways

Cycle Cellulaire, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy