ARAP1 anticorps (AA 1190-1450)

N° du produit ABIN302078

Détail du produit anti-ARAP1 anticorps

Antigène: ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))

Épitope: AA 1190-1450

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ARAP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificité: The antibody ARAP1-2 reacts with C-terminal part of ARAP1 (intracellular epitope), a 160 kDa adaptor protein.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1

Clone: ARAP1-2

Isotype: IgG1

Information d'application

Indications d'application: Western blotting: Recommended dilution: 2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-ARAP1 (ABIN302078)

Símová, Klíma, Cermak, Sourková, Andera: "Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane." dans: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 3, pp. 423-36, (2008) (PubMed).

Détails sur ARAP1

Antigène: ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))

Autre désignation: ARAP1 (ARAP1 Produits)

Synonymes: anticorps CENTD2, anticorps ARAP1, anticorps Ci-ArfGAP-8, anticorps 2410002L19Rik, anticorps Centd2, anticorps mKIAA0782, anticorps ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1, anticorps centaurin, delta 2, anticorps ARAP1, anticorps centd2, anticorps Arap1

Sujet: ArfGAP with RhoGAP domain, ankyrin repeat and PH d,ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.,CED2, CENTD2

ID gène: 116985

UniProt: Q96P48