FLI1 anticorps (AA 107-216)
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- Antigène Voir toutes FLI1 Anticorps
- FLI1 (Friend Leukemia Virus Integration 1 (FLI1))
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Épitope
- AA 107-216
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FLI1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Purification
- Protein G affinity chromatography
- Immunogène
- Human partial recombinant protein (amino acids 107-216) was used as the immunogen for this FLI1 antibody.
- Clone
- FLVI1-1
- Isotype
- IgG
- Top Product
- Discover our top product FLI1 Anticorps primaire
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- Indications d'application
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FLI1 antibody to be titered up or down for optimal performance.\. Western blot: 1-2 μg/m,l,FACS: 0.5-1 μg/10^6 cells,IF: 1-2 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the FLI1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- FLI1 (Friend Leukemia Virus Integration 1 (FLI1))
- Autre désignation
- FLI1 (FLI1 Produits)
- Synonymes
- anticorps EWSR2, anticorps SIC-1, anticorps FLI1, anticorps fli, anticorps Xfli, anticorps fli1, anticorps Xfli1, anticorps fli-1, anticorps Xfli-1, anticorps MGC121593, anticorps Fli-1, anticorps Sic1, anticorps cb855, anticorps wu:fc45b11, anticorps xlfli, anticorps Fli-1 proto-oncogene, ETS transcription factor, anticorps Fli-1 proto-oncogene, ETS transcription factor S homeolog, anticorps Friend leukemia integration 1, anticorps Fli-1 proto-oncogene, ETS transcription factor a, anticorps Fli-1 proto-oncogene, ETS transcription factor L homeolog, anticorps FLI1, anticorps Fli1, anticorps fli1.S, anticorps fli1, anticorps fli1a, anticorps fli1.L
- Sujet
- Friend leukemia integration 1 is a member of the ETS family of DNA binding transcription factors that is involved in cellular proliferation and tumorigenesis. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing's Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi's Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.
- ID gène
- 2313
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