HLA-DR anticorps

N° du produit ABIN3026340

L’anticorps anti-HLA-DR Monoclonal Souris est utilisé pour la détection de HLA-DR dans des échantillons de Humain, Cat et Boeuf (Vache). Il a été validé pour FACS et IF.

Aperçu rapide pour HLA-DR anticorps (ABIN3026340)

Antigène: HLA-DR

Reactivité: Humain, Cat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-DR est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 169-1B5-2

Détail du produit anti-HLA-DR anticorps

Attributs du produit: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Purification: Protein G affinity chromatography

Immunogène: Human peripheral blood leukocytes were used as the immunogen for the HLA-DR antibody.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal dilution of the HLA-DR antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the HLA-DR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur HLA-DR

Antigène: HLA-DR

Autre désignation: HLA-DR (MHC II)

Sujet: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36  kDa alpha (heavy) chain and a 28  kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response